The Journey of Probiotics: Do Probiotic Supplements Survive Stomach Acid?

The Journey of Probiotics: Do Probiotic Supplements Survive Stomach Acid?

Are you bewildered by the wide variety of probiotic options available in stores? You’ve probably heard about their amazing benefits and are eager to incorporate them into your life. But can these beneficial microorganisms survive the harsh journey through your stomach and reach your intestines to deliver their magic? If not, why invest in probiotics?

This blog holds the answer to this pressing doubt. Explore the fascinating journey of probiotics, from the moment you swallow them to their arrival in your gut. You’ll also learn the challenges they face and how you can ensure probiotics survive stomach acid. So, get ready to witness the fate of your probiotics!

What are probiotics?

Probiotics are live microorganismsmostly bacteria and yeaststhat, when consumed in adequate amounts, can offer a range of health benefits. They're not just any microbes; they're specific strains that are shown to improve human health. Think of them as tiny allies working within your gut.

Probiotics are classified by their genus, species, and strain. For example, Lactobacillus rhamnosus GG tells us the genus (Lactobacillus), the species (rhamnosus), and the specific strain (GG). This precise classification is important because different strains can have varying effects on the body.

These beneficial microbes play a crucial role in maintaining gut health. From contributing to a balanced gut microbiome to keeping harmful bacteria at bay and reducing infection risks, probiotics are essential for proper digestion, nutrient absorption, and a robust immune system. A healthy gut microbiome is also linked to other aspects of health, including mental well-being and skin health, and it can even reduce the risk of certain chronic diseases.

Check out how probiotics can help in your weight loss journey by watching the video below.


Probiotics can be found in various sources:

  • Fermented foods: Foods like yoghurt with live cultures, kefir, kombucha, sauerkraut, kimchi, miso, tempeh, and some aged cheeses naturally contain these beneficial microorganisms.

  • Probiotic supplements: They offer a concentrated dose of specific strains, often selected for their specific health benefits. Probiotic supplements are available as pills, capsules, tablets, and powders. 

Next, let's see what factors could complicate the journey of these helpful little critters!

Factors affecting probiotic survival

Do you want to end up choosing a probiotic that has little to no effect on your gut? You could be swallowing those tiny helpers, thinking that you're doing something good for your body. But the truth is that they might not even make it to where they need to be. That's because probiotics face several challenges on their journey to the gut:

  • Antibiotics and antimicrobials: These are designed to kill harmful bacteria and microbes and effectively treat infections. But unfortunately, they often can't distinguish between good bacteria and bad bacteria. So, antibiotics can inadvertently destroy beneficial bacteria, impacting their survival and disrupting your gut microbiome.

  • Acidity: The stomach is a highly acidic environment, which is designed to kill harmful bacteria that might enter the body through food or drink. However, this acidity can also be a major hurdle for probiotics, as many strains are simply not able to survive the low pH of the stomach.  

  • Heat: Probiotics are live organisms, and like any living thing, they can be sensitive to temperature extremes. Exposure to heat can kill probiotics, rendering them ineffective. This is why it's important to store probiotic supplements properly, usually in a cool, dry place, and to check the label for specific storage instructions.  

  • Alcohol: Excessive alcohol consumption can damage the gut lining and disrupt the balance of the gut microbiome. This can make it more difficult for probiotics to survive and colonise the gut.

  • Dysbiosis: If your gut microbiome is already imbalanced (a condition called dysbiosis), it can be more challenging for new probiotic bacteria to establish themselves. The beneficial bacteria must compete with the existing, potentially harmful bacteria for resources and space.

Once you get the hang of what stomach acid does, you'll see why the survival of probiotics becomes a thrilling ride, almost like a survival game for these little guys!

Understanding stomach acid

Stomach acid, primarily composed of hydrochloric acid, is a highly acidic digestive fluid. Its pH typically ranges from 1.5 to 3.5, making it a harsh environment. But what’s the purpose of this highly acidic environment in the stomach? Let’s look at the functions of the stomach acid:

  • Digestion: Stomach acid aids in the digestion of food, particularly the breakdown of proteins. It activates digestive enzymes like pepsin, which significantly dismantle proteins into smaller, more manageable components that the body can readily absorb. This process is vital for proper nutrition since proteins are essential for building and repairing body tissues. 

  • Defends pathogens: Stomach acid acts as one of the body's first lines of defence against ingested pathogens. This high acidity creates a hostile environment for many harmful bacteria and other microorganisms that might enter the body through food or drink. It effectively neutralises many of these potential invaders, preventing them from causing illness

Stomach acid acts like a gatekeeper, allowing essential nutrients to pass while blocking harmful substances. This raises an intriguing question: Can probiotics pass through the highly acidic pH of the stomach?

Do probiotics survive stomach acid?

The answer to whether probiotics can survive stomach acid isn't a simple yes or no. It depends. While some probiotic strains are robust and acid-resistant, able to withstand the fiery gauntlet of stomach acid, others are more vulnerable.

While crucial for digestion and defence, the stomach's high acidity can be a major hurdle for many probiotics. This highly acidic environment can kill a significant portion of the probiotic bacteria, reducing their effectiveness and diminishing their potential benefits once they reach the intestines.  

It's a double-edged sword: the mechanism that protects you from harmful bacteria can also inadvertently affect the beneficial probiotic bacteria you're trying to introduce to your gut. So, the challenge lies in ensuring that the probiotics you consume are strong enough to make it through this acidic obstacle course.

But don't worry, there's hope as you explore which probiotics have what it takes to beat the odds.

Probiotics that survive stomach acid

Not all probiotic strains are created equal. While some beneficial bacteria might perish before reaching their destination, others have the inherent ability to withstand harsh conditions. They are naturally better equipped to survive the acidic environment and make it to the intestines, where they can exert their beneficial effects

For instance, strains like Bacillus coagulans possess a protective spore coat that allows them to withstand extreme conditions, ensuring their survival through the stomach. Here are other probiotic strains that have demonstrated a greater capacity to survive stomach acid:

  • Lactobacillus rhamnosus GG

  • Lactobacillus casei Shirota

  • Lactobacillus acidophilus Rosell-52

  • Lactobacillus rhamnosus Rosell-11 

  • Bifidobacterium longum

  • Bifidobacterium animalis subsp. lactis BB-12

It’s important to note that this list includes commonly studied strains, but more research is needed to understand the acid resistance of many other probiotic strains. 

But how can you ensure your probiotics pass this tough test of survival? Stick around, because we've got some game-changing strategies coming up next!

Strategies to enhance probiotic survival

So, you might be thinking, ‘If stomach acid is so harsh, are all probiotics ineffective?’ Absolutely not! While the stomach acid barrier is a real challenge, you can combat its effects and maximise the chances of your probiotics reaching your gut alive and well. Here are some proven strategies to enhance probiotic survival:

  • Encapsulation: The probiotic shield: Encapsulation technology is a game-changer for probiotic survival. Some probiotic supplements utilise targeted release technology, where the delicate probiotic bacteria are protected by a micro-shield. This micro-shield is designed to resist stomach acid, acting like a protective suit for the probiotics as they travel through the stomach. The micro-shield then releases the probiotics in the more neutral environment of the intestines, ensuring they arrive at their destination intact and ready to work.

  • Regular intake: Building a stronghold: Regularly taking probiotics establishes a consistent population of beneficial bacteria in your gut. Think of it as building a strong and resilient colony of gut allies. Regular intake can help offset the losses that may occur due to stomach acid and other factors, ensuring a steady supply of beneficial bacteria.

  • Timing: The strategic moment: When you take your probiotics can significantly impact their survival. Taking them between meals or on an empty stomach is often recommended. When your stomach is full of food, it produces more acid to aid digestion. This food can buffer stomach acid, potentially reducing its effectiveness against probiotics. Taking them when your stomach is relatively empty can help them pass through more quickly, reducing their exposure to the harsh acid. Many experts recommend taking probiotics 30 minutes before a meal or just before bed for better survival rates.

  • Dosage: The power in numbers: The number of live probiotic cells in a dose, measured in Colony Forming Units (CFUs), also plays a role in survival. A higher CFU count can increase the likelihood that enough probiotics will survive the journey to the gut. Consult your doctor or a registered dietitian to determine the optimal CFU count for your needs.

  • Strain selection: Targeted approach: Some probiotic strains are better suited for specific health conditions. Research has shown that certain strains are more effective for particular issues like irritable bowel syndrome (IBS), while others are better for immune support. Selecting probiotic strains tailored to your specific health needs can enhance their effectiveness.

  • Synbiotics: The power duo: Synbiotics combine probiotics with prebiotics. Prebiotics are non-digestible fibers that act as food for the probiotics, helping them to thrive and colonise the gut more effectively. This combination can significantly enhance the usefulness of probiotics.

So, you're geared with knowledge, but how do you actually know if these tiny organisms are doing their magic in your gut?

How do you know if your probiotics have survived?

You've done your research, chosen a high-quality probiotic, and are following all the tips to maximise its survival. But still, a nagging question remains: Are those probiotics actually working? How do you know if those tiny helpers have survived the stomach acid and reached your gut? While there's no foolproof way to track the journey of each individual probiotic, there are some ways to get a sense of whether they're doing their job:

  • Gut microbiome testing: At-home gut microbiome tests have become increasingly popular. These tests can provide insights into the overall composition of your gut microbiome, identifying the types of bacteria present. While these tests can't directly tell you if the probiotics from your specific supplement have survived, they can give you a general picture of your gut health and whether it's trending in a positive direction. Changes in your gut microbiome profile after starting a probiotic regimen can indirectly indicate their influence.

  • Reflect on how you feel: The most practical way to understand probiotic effectiveness is to assess its impact on you. Have you noticed improvements in your digestive health? Are you more regular? Have other symptoms you were hoping to address started to improve? While these observations aren't scientific proof, they can hint at probiotic survival. Remember, it can take time to see noticeable changes, so be patient and consistent with your probiotic routine.

  • Human clinical trials: Clinical trials offer substantial evidence regarding the efficacy and survival capabilities of specific probiotic strains. These studies test how well a strain survives through the digestive tract and adapts within the gut. When researching probiotic supplements, look for products that are backed by solid clinical evidence. This ensures that your chosen product has a proven track record of survival and effectiveness.

The survival of probiotics through stomach acid is a critical factor influencing their efficacy. After all, these tiny heroes can't do their job if they don't make it to the gut alive! The journey of probiotics is challenging, but with the right choices, you can ensure that they reach their destination and deliver their beneficial effects. 

Choosing high-quality probiotics with proven survivability is key. Look for products that contain well-researched, acid-resistant strains and consider factors like encapsulation technology. Remember, a thriving gut is essential for overall health and well-being.

Ready to give your gut the support it deserves? Check out The Good Bug's range of probiotic supplements, formulated with carefully selected strains to maximise their effectiveness. Explore The Good Bug's offerings and discover the difference that truly thriving probiotics can make!

References

https://www.optibacprobiotics.com/learning-lab/about/probiotics/how-probiotics-survive-stomach-acid-digestion

https://www.rupahealth.com/post/do-probiotics-survive-stomach-acid

https://www.perkii.com/blogs/news/do-probiotics-survive-in-the-stomach

https://pursuit.unimelb.edu.au/articles/making-the-most-of-probiotics

Back to blog